There is no established dosage for melatonin that is widely accepted. In addition, experts note that
most brands contain impurities that cannot be characterized, as well as dissimilar amounts of actual
When buying in America, please note that the U.S. Food and Drug Administration does not strictly regulate herbs and supplements.
There is no guarantee of strength, purity or safety of products, and effects may vary.
You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.
Below are dosages used by researchers exploring various disorders.
(Summarized from the
|Adults (18 years and older)|
|Alzheimer's disease (sleep disturbances)||0.5||nightly, 1 hr before bedtime|
|Bipolar disorder (sleep disturbances)||10||nightly by mouth|
|Cancer ||10 to 50,|
most commonly 20
|Circadian rhythm entraining (in blind persons)||5 to10||nightly|
|Critical Illness / ICU sleep disturbance||3||nightly|
|Delayed sleep phase syndrome||5||5 hrs before bedtime|
|Depression (sleep disturbances)||5||nightly|
|Headache prevention||5 to 10||nightly|
|Hypertension||1 to 3||short periods of time|
|Insomnia in the elderly||3 to 5||30 - 120 min before bedtime|
|Insomnia of unknown origin (in the non-elderly)||1 to 5||nightly|
|Jet lag||0.1 to 0.5,|
5 and 8
|Target bedtime at the destination|
|Schizophrenia (sleep disturbances)||2||(not stated)|
|Seasonal affective disorder||0.25 to 5||daily|
|Sleep enhancement in healthy people||0.1 to 6||30 - 60 minutes before bedtime|
|Children (younger than 18 years)|
There is limited study of melatonin supplements in children, and safety is not established.
Use of melatonin should be discussed with the child's physician prior to starting.
|Circadian rhythm entraining in blind children||2.5 to 10||nightly|
|Preoperative anxiety||0.1, 0.25 or 0.5 per kilogram (of child’s weight?)||(not stated)|
|Seizure disorder in children||5 to 10||nightly|
|Sleep disturbances in children with neuro-psychiatric disorders (mental retardation, autism, psychiatric disorders)||0.5 to 10||nightly|
Want more? See the
Google News Archive for melatonin and dosage.
Two bottles of melatonin in our most popular sizes, and a free sleep mask. Regularly $14.95.
THE FINE PRINT: The content presented in this website is for informational purposes only.
Before taking this or any other health supplement or therapy, consult your healthcare professional.
Even mild supplements can have varying effects on individuals, and can conflict with your existing medications and diet.
See additional information.
- WORLDWIDE LABS
"I just had to send you a message of thanks, for your detailed response to my query re: Melatonin and alcohol. It certainly put my mind at ease. Actually, I neither take melatonin nor alcohol daily. But, I needed to know, just in case. If your company has a mailing list, please put me on it. Thanks again." - M.M., Mexico
"Thank you so much for the Melatonin. Have been insomniac in the last ten years. As I have extremely low alcohol tolerance, it is rather of relief to have something else that gets me comfortable sleep. I will be dreaming of skiing in Snowbird [in Utah near WWL] tonight! Ciao." - S., Japan
"Thank you WWL for your prompt service. I live in Australia and I received my order within 6 days. Your melatonin is the best I have used and I have used several different brands before, no hang-over next day and I'm sleeping much better." - B from Sidney, Australia
"For many years I have woken around 3am and found difficulty getting back to sleep again. I now take two Melatonin 1.5gm Sustained Release tablets every night and have had no more broken nights... Thank you WWL!" - H.C., United Kingdom